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Gender Matters in Limb Salvage: What the BEST-CLI Trial Teaches Us About Female Patients and Vascular Surgery

In the groundbreaking BEST-CLI (Best Endovascular vs. Best Surgical Therapy in Patients with Critical Limb Ischemia) trial, a surprising and important observation emerged: female patients had fewer limb amputations than their male counterparts.

Dr. Katharine McGinigle, vascular surgeon-scientist and a board member of the American Limb Preservation Society (ALPS), led the gender-based secondary analysis of the trial. Here’s what they found:

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ALPS at PODOCON 2025: Strengthening International Collaboration and Multidisciplinary Limb Preservation

The American Limb Preservation Society (ALPS) marked its presence at PODOCON 2025 in Bangalore, India, reaffirming its mission to eliminate preventable amputations worldwide. The visit underscored ALPS’s commitment to advancing education and promoting the benefits of multidisciplinary teams in diabetic foot care in regions facing high burdens of diabetes-related complications.

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Leading the Global Charge in Diabetic Foot Education: The American Limb Preservation Society

New publication in May Special Edition of the Limb Preservation Journal highlights ALPS’ global impact. The article in the special issue outlines the position and educational initiatives being undertaken in 2025 by the American Limb Preservation Society, a partner member, along with Wounds Canada, of the Limb Preservations Alliance. It highlights global outreach programs and collaborations in 2025.

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