Introduction
In addition to the preventative benefits of appropriate medication in high-risk patients with diabetes and/or vascular compromise, working with a patient’s primary care provider to ensure medical optimization of comorbid conditions is a cornerstone of preoperative management to help reduce the risk of postoperative complications. Accordingly, we have a compiled a brief reference resource list ranging from recent studies on antithrombotic medications and lipid-lowering therapies to the latest meta-analyses and literature on hypertension and diabetes management.
Antithrombotic therapy
Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomized, double-blind, placebo-controlled trial.
Major adverse limb events and mortality in patients with peripheral artery disease: the COMPASS trial.
Safety and efficacy of vorapaxar in secondary prevention of atherosclerotic disease: a meta-analysis of randomized control trials.
Ticagrelor for prevention of ischemic events after myocardial infarction in patients with peripheral artery disease.
Peripheral revascularization in patients with peripheral artery disease with vorapaxar: insights from the TRA 2oP-TIMI 50 trial.
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomized trials.
Prevention of serious vascular events by aspirin amongst patients with peripheral arterial disease: randomized, double-blind trial.
Lipid-Lowering Therapy
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Association of statin dose with amputation and survival in patients with peripheral artery disease.
Association between intensity of statin therapy and mortality in patients with atherosclerotic cardiovascular disease.
High-intensity statin therapy is associated with improved survival in patients with peripheral artery disease.
Use of angiotensin-converting enzyme inhibitors and freedom from amputation after lower extremity revascularization
Intensive vs. standard blood pressure control and cardiovascular disease outcomes in adults aged > 75 years: a randomized clinical trial.
Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the justification for use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER).
Lipid-lowering for peripheral arterial disease of the lower limb.
Cochrane Database Syst Rev. 2007;2007(4):CD000123. doi: 10:1002/14651858.CD000123.pub2
Visit Resource
Visit Resource